What is the difference between 2x4 and 2x4HD?

While these 2 platforms hold a similar name, they actually couldn't be more different! :-)
The 2x4HD has 10x more processing power, USB audio streaming and a lot more control features. It's the next generation platform based on XMOS + SHARC DSP. Here is a good summary table:
 

miniDSP 2x4

miniDSP 2x4HD

28/56bit Fixed point DSP Engine ADSP12489 400MHz Sharc floating point DSP
24 bit ADC/DAC resolution 24 bit ADC/DAC resolution
Unbalanced analog audio inputs switchable with a jumper between 0.9Vrms and 2Vrms Unbalanced analog audio inputs switchable with a jumper between 4Vrms and 2Vrms
Digital I/O: I2S in/out Digital I/O: USB audio & Toslink (44.1~192kHz), I2S I/O (not enabled yet)
Unbalanced analog audio outputs: Max 0.9Vrms Unbalanced analog audio outputs: Max 2Vrms
Plug&Play USB driver and real time Software configuration using miniDSP plug-ins Plug&Play USB driver and real time Software configuration using miniDSP plug-ins
N/A Asynchronous USB Audio Class 2 Bidirectional streaming with ASIO drivers under Windows, driverless under MAC Osx
Device does not required a PC once configured Device does not required a PC once configured
Software: miniDSP 2x4 plug-ins Software: miniDSP 2x4 HD1 plug-in
Control: Volume control by potentiometer on 3pin header Control: IR remote + multicolor LED for preset indication
USB self powered device and wide range of DC power options (4.5 to 24VDC) External single 12V supply (UK/EU/US/AU adaptors provided)
Price: 105USD Price: 205USD

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